diff --git a/src/yuzu/CMakeLists.txt b/src/yuzu/CMakeLists.txt
index f9ca2948e..36714f55e 100644
--- a/src/yuzu/CMakeLists.txt
+++ b/src/yuzu/CMakeLists.txt
@@ -27,6 +27,8 @@ add_executable(yuzu
     configuration/configure_graphics.h
     configuration/configure_input.cpp
     configuration/configure_input.h
+    configuration/configure_mouse_advanced.cpp
+    configuration/configure_mouse_advanced.h
     configuration/configure_system.cpp
     configuration/configure_system.h
     configuration/configure_web.cpp
@@ -76,6 +78,7 @@ set(UIS
     configuration/configure_general.ui
     configuration/configure_graphics.ui
     configuration/configure_input.ui
+    configuration/configure_mouse_advanced.ui
     configuration/configure_system.ui
     configuration/configure_web.ui
     hotkeys.ui
diff --git a/src/yuzu/configuration/configure_mouse_advanced.cpp b/src/yuzu/configuration/configure_mouse_advanced.cpp
new file mode 100644
index 000000000..8cfcd1679
--- /dev/null
+++ b/src/yuzu/configuration/configure_mouse_advanced.cpp
@@ -0,0 +1,211 @@
+// Copyright 2016 Citra Emulator Project
+// Licensed under GPLv2 or any later version
+// Refer to the license.txt file included.
+
+#include <algorithm>
+#include <memory>
+#include <utility>
+#include <QKeyEvent>
+#include <QMenu>
+#include <QMessageBox>
+#include <QTimer>
+#include "common/assert.h"
+#include "common/param_package.h"
+#include "input_common/main.h"
+#include "ui_configure_mouse_advanced.h"
+#include "yuzu/configuration/config.h"
+#include "yuzu/configuration/configure_mouse_advanced.h"
+
+static QString getKeyName(int key_code) {
+    switch (key_code) {
+    case Qt::Key_Shift:
+        return QObject::tr("Shift");
+    case Qt::Key_Control:
+        return QObject::tr("Ctrl");
+    case Qt::Key_Alt:
+        return QObject::tr("Alt");
+    case Qt::Key_Meta:
+        return "";
+    default:
+        return QKeySequence(key_code).toString();
+    }
+}
+
+static QString ButtonToText(const Common::ParamPackage& param) {
+    if (!param.Has("engine")) {
+        return QObject::tr("[not set]");
+    } else if (param.Get("engine", "") == "keyboard") {
+        return getKeyName(param.Get("code", 0));
+    } else if (param.Get("engine", "") == "sdl") {
+        if (param.Has("hat")) {
+            return QString(QObject::tr("Hat %1 %2"))
+                .arg(param.Get("hat", "").c_str(), param.Get("direction", "").c_str());
+        }
+        if (param.Has("axis")) {
+            return QString(QObject::tr("Axis %1%2"))
+                .arg(param.Get("axis", "").c_str(), param.Get("direction", "").c_str());
+        }
+        if (param.Has("button")) {
+            return QString(QObject::tr("Button %1")).arg(param.Get("button", "").c_str());
+        }
+        return QString();
+    } else {
+        return QObject::tr("[unknown]");
+    }
+}
+
+ConfigureMouseAdvanced::ConfigureMouseAdvanced(QWidget* parent)
+    : QDialog(parent), ui(std::make_unique<Ui::ConfigureMouseAdvanced>()),
+      timeout_timer(std::make_unique<QTimer>()), poll_timer(std::make_unique<QTimer>()) {
+    ui->setupUi(this);
+    setFocusPolicy(Qt::ClickFocus);
+
+    button_map = {
+        ui->left_button, ui->right_button, ui->middle_button, ui->forward_button, ui->back_button,
+    };
+
+    for (int button_id = 0; button_id < Settings::NativeMouseButton::NumMouseButtons; button_id++) {
+        if (!button_map[button_id])
+            continue;
+        button_map[button_id]->setContextMenuPolicy(Qt::CustomContextMenu);
+        connect(button_map[button_id], &QPushButton::released, [=]() {
+            handleClick(
+                button_map[button_id],
+                [=](const Common::ParamPackage& params) { buttons_param[button_id] = params; },
+                InputCommon::Polling::DeviceType::Button);
+        });
+        connect(button_map[button_id], &QPushButton::customContextMenuRequested,
+                [=](const QPoint& menu_location) {
+                    QMenu context_menu;
+                    context_menu.addAction(tr("Clear"), [&] {
+                        buttons_param[button_id].Clear();
+                        button_map[button_id]->setText(tr("[not set]"));
+                    });
+                    context_menu.addAction(tr("Restore Default"), [&] {
+                        buttons_param[button_id] =
+                            Common::ParamPackage{InputCommon::GenerateKeyboardParam(
+                                Config::default_mouse_buttons[button_id])};
+                        button_map[button_id]->setText(ButtonToText(buttons_param[button_id]));
+                    });
+                    context_menu.exec(button_map[button_id]->mapToGlobal(menu_location));
+                });
+    }
+
+    connect(ui->buttonClearAll, &QPushButton::released, [this] { ClearAll(); });
+    connect(ui->buttonRestoreDefaults, &QPushButton::released, [this]() { restoreDefaults(); });
+
+    timeout_timer->setSingleShot(true);
+    connect(timeout_timer.get(), &QTimer::timeout, [this]() { setPollingResult({}, true); });
+
+    connect(poll_timer.get(), &QTimer::timeout, [this]() {
+        Common::ParamPackage params;
+        for (auto& poller : device_pollers) {
+            params = poller->GetNextInput();
+            if (params.Has("engine")) {
+                setPollingResult(params, false);
+                return;
+            }
+        }
+    });
+
+    loadConfiguration();
+    resize(0, 0);
+}
+
+void ConfigureMouseAdvanced::applyConfiguration() {
+    std::transform(buttons_param.begin(), buttons_param.end(),
+                   Settings::values.mouse_buttons.begin(),
+                   [](const Common::ParamPackage& param) { return param.Serialize(); });
+}
+
+void ConfigureMouseAdvanced::loadConfiguration() {
+    std::transform(Settings::values.mouse_buttons.begin(), Settings::values.mouse_buttons.end(),
+                   buttons_param.begin(),
+                   [](const std::string& str) { return Common::ParamPackage(str); });
+    updateButtonLabels();
+}
+
+void ConfigureMouseAdvanced::restoreDefaults() {
+    for (int button_id = 0; button_id < Settings::NativeMouseButton::NumMouseButtons; button_id++) {
+        buttons_param[button_id] = Common::ParamPackage{
+            InputCommon::GenerateKeyboardParam(Config::default_mouse_buttons[button_id])};
+    }
+
+    updateButtonLabels();
+}
+
+void ConfigureMouseAdvanced::ClearAll() {
+    for (int i = 0; i < Settings::NativeMouseButton::NumMouseButtons; ++i) {
+        if (button_map[i] && button_map[i]->isEnabled())
+            buttons_param[i].Clear();
+    }
+
+    updateButtonLabels();
+}
+
+void ConfigureMouseAdvanced::updateButtonLabels() {
+    for (int button = 0; button < Settings::NativeMouseButton::NumMouseButtons; button++) {
+        button_map[button]->setText(ButtonToText(buttons_param[button]));
+    }
+}
+
+void ConfigureMouseAdvanced::handleClick(
+    QPushButton* button, std::function<void(const Common::ParamPackage&)> new_input_setter,
+    InputCommon::Polling::DeviceType type) {
+    button->setText(tr("[press key]"));
+    button->setFocus();
+
+    const auto iter = std::find(button_map.begin(), button_map.end(), button);
+    ASSERT(iter != button_map.end());
+    const auto index = std::distance(button_map.begin(), iter);
+    ASSERT(index < Settings::NativeButton::NumButtons && index >= 0);
+
+    input_setter = new_input_setter;
+
+    device_pollers = InputCommon::Polling::GetPollers(type);
+
+    // Keyboard keys can only be used as button devices
+    want_keyboard_keys = type == InputCommon::Polling::DeviceType::Button;
+
+    for (auto& poller : device_pollers) {
+        poller->Start();
+    }
+
+    grabKeyboard();
+    grabMouse();
+    timeout_timer->start(5000); // Cancel after 5 seconds
+    poll_timer->start(200);     // Check for new inputs every 200ms
+}
+
+void ConfigureMouseAdvanced::setPollingResult(const Common::ParamPackage& params, bool abort) {
+    releaseKeyboard();
+    releaseMouse();
+    timeout_timer->stop();
+    poll_timer->stop();
+    for (auto& poller : device_pollers) {
+        poller->Stop();
+    }
+
+    if (!abort) {
+        (*input_setter)(params);
+    }
+
+    updateButtonLabels();
+    input_setter = boost::none;
+}
+
+void ConfigureMouseAdvanced::keyPressEvent(QKeyEvent* event) {
+    if (!input_setter || !event)
+        return;
+
+    if (event->key() != Qt::Key_Escape) {
+        if (want_keyboard_keys) {
+            setPollingResult(Common::ParamPackage{InputCommon::GenerateKeyboardParam(event->key())},
+                             false);
+        } else {
+            // Escape key wasn't pressed and we don't want any keyboard keys, so don't stop polling
+            return;
+        }
+    }
+    setPollingResult({}, true);
+}
diff --git a/src/yuzu/configuration/configure_mouse_advanced.h b/src/yuzu/configuration/configure_mouse_advanced.h
new file mode 100644
index 000000000..f897d9044
--- /dev/null
+++ b/src/yuzu/configuration/configure_mouse_advanced.h
@@ -0,0 +1,67 @@
+// Copyright 2016 Citra Emulator Project
+// Licensed under GPLv2 or any later version
+// Refer to the license.txt file included.
+
+#pragma once
+
+#include <memory>
+#include <QDialog>
+#include <QWidget>
+#include <boost/optional.hpp>
+#include "core/settings.h"
+
+class QCheckBox;
+class QPushButton;
+class QTimer;
+
+namespace Ui {
+class ConfigureMouseAdvanced;
+}
+
+class ConfigureMouseAdvanced : public QDialog {
+    Q_OBJECT
+
+public:
+    explicit ConfigureMouseAdvanced(QWidget* parent);
+
+    void applyConfiguration();
+
+private:
+    std::unique_ptr<Ui::ConfigureMouseAdvanced> ui;
+
+    /// This will be the the setting function when an input is awaiting configuration.
+    boost::optional<std::function<void(const Common::ParamPackage&)>> input_setter;
+
+    std::array<QPushButton*, Settings::NativeMouseButton::NumMouseButtons> button_map;
+    std::array<Common::ParamPackage, Settings::NativeMouseButton::NumMouseButtons> buttons_param;
+
+    std::vector<std::unique_ptr<InputCommon::Polling::DevicePoller>> device_pollers;
+
+    std::unique_ptr<QTimer> timeout_timer;
+    std::unique_ptr<QTimer> poll_timer;
+
+    /// A flag to indicate if keyboard keys are okay when configuring an input. If this is false,
+    /// keyboard events are ignored.
+    bool want_keyboard_keys = false;
+
+    /// Load configuration settings.
+    void loadConfiguration();
+    /// Restore all buttons to their default values.
+    void restoreDefaults();
+    /// Clear all input configuration
+    void ClearAll();
+
+    /// Update UI to reflect current configuration.
+    void updateButtonLabels();
+
+    /// Called when the button was pressed.
+    void handleClick(QPushButton* button,
+                     std::function<void(const Common::ParamPackage&)> new_input_setter,
+                     InputCommon::Polling::DeviceType type);
+
+    /// Finish polling and configure input using the input_setter
+    void setPollingResult(const Common::ParamPackage& params, bool abort);
+
+    /// Handle key press events.
+    void keyPressEvent(QKeyEvent* event) override;
+};
diff --git a/src/yuzu/configuration/configure_mouse_advanced.ui b/src/yuzu/configuration/configure_mouse_advanced.ui
new file mode 100644
index 000000000..08245ecf0
--- /dev/null
+++ b/src/yuzu/configuration/configure_mouse_advanced.ui
@@ -0,0 +1,261 @@
+<?xml version="1.0" encoding="UTF-8"?>
+<ui version="4.0">
+ <class>ConfigureMouseAdvanced</class>
+ <widget class="QDialog" name="ConfigureMouseAdvanced">
+  <property name="geometry">
+   <rect>
+    <x>0</x>
+    <y>0</y>
+    <width>250</width>
+    <height>261</height>
+   </rect>
+  </property>
+  <property name="windowTitle">
+   <string>Configure Mouse</string>
+  </property>
+  <layout class="QVBoxLayout" name="verticalLayout">
+   <item>
+    <widget class="QGroupBox" name="gridGroupBox">
+     <property name="title">
+      <string>Mouse Buttons</string>
+     </property>
+     <layout class="QGridLayout" name="gridLayout">
+      <item row="0" column="4">
+       <spacer name="horizontalSpacer_2">
+        <property name="orientation">
+         <enum>Qt::Horizontal</enum>
+        </property>
+        <property name="sizeType">
+         <enum>QSizePolicy::Fixed</enum>
+        </property>
+        <property name="sizeHint" stdset="0">
+         <size>
+          <width>20</width>
+          <height>20</height>
+         </size>
+        </property>
+       </spacer>
+      </item>
+      <item row="0" column="3">
+       <layout class="QVBoxLayout" name="verticalLayout_4">
+        <item>
+         <layout class="QHBoxLayout" name="horizontalLayout_3">
+          <item>
+           <widget class="QLabel" name="label_3">
+            <property name="text">
+             <string>Right:</string>
+            </property>
+           </widget>
+          </item>
+         </layout>
+        </item>
+        <item>
+         <widget class="QPushButton" name="right_button">
+          <property name="minimumSize">
+           <size>
+            <width>75</width>
+            <height>0</height>
+           </size>
+          </property>
+          <property name="text">
+           <string/>
+          </property>
+         </widget>
+        </item>
+       </layout>
+      </item>
+      <item row="0" column="0">
+       <spacer name="horizontalSpacer">
+        <property name="orientation">
+         <enum>Qt::Horizontal</enum>
+        </property>
+        <property name="sizeType">
+         <enum>QSizePolicy::Fixed</enum>
+        </property>
+        <property name="sizeHint" stdset="0">
+         <size>
+          <width>20</width>
+          <height>20</height>
+         </size>
+        </property>
+       </spacer>
+      </item>
+      <item row="2" column="1">
+       <layout class="QVBoxLayout" name="verticalLayout_3">
+        <item>
+         <layout class="QHBoxLayout" name="horizontalLayout_2">
+          <item>
+           <widget class="QLabel" name="label_2">
+            <property name="text">
+             <string>Middle:</string>
+            </property>
+           </widget>
+          </item>
+         </layout>
+        </item>
+        <item>
+         <widget class="QPushButton" name="middle_button">
+          <property name="text">
+           <string/>
+          </property>
+         </widget>
+        </item>
+       </layout>
+      </item>
+      <item row="3" column="1">
+       <layout class="QVBoxLayout" name="verticalLayout_5">
+        <item>
+         <layout class="QHBoxLayout" name="horizontalLayout_4">
+          <item>
+           <widget class="QLabel" name="label_4">
+            <property name="minimumSize">
+             <size>
+              <width>54</width>
+              <height>0</height>
+             </size>
+            </property>
+            <property name="text">
+             <string>Back:</string>
+            </property>
+           </widget>
+          </item>
+         </layout>
+        </item>
+        <item>
+         <widget class="QPushButton" name="back_button">
+          <property name="text">
+           <string/>
+          </property>
+         </widget>
+        </item>
+       </layout>
+      </item>
+      <item row="0" column="1">
+       <layout class="QVBoxLayout" name="verticalLayout_2">
+        <item>
+         <layout class="QHBoxLayout" name="horizontalLayout">
+          <item>
+           <widget class="QLabel" name="label">
+            <property name="text">
+             <string>Left:</string>
+            </property>
+           </widget>
+          </item>
+         </layout>
+        </item>
+        <item>
+         <widget class="QPushButton" name="left_button">
+          <property name="minimumSize">
+           <size>
+            <width>75</width>
+            <height>0</height>
+           </size>
+          </property>
+          <property name="text">
+           <string/>
+          </property>
+         </widget>
+        </item>
+       </layout>
+      </item>
+      <item row="3" column="3">
+       <layout class="QVBoxLayout" name="verticalLayout_6">
+        <item>
+         <layout class="QHBoxLayout" name="horizontalLayout_5">
+          <item>
+           <widget class="QLabel" name="label_5">
+            <property name="text">
+             <string>Forward:</string>
+            </property>
+           </widget>
+          </item>
+         </layout>
+        </item>
+        <item>
+         <widget class="QPushButton" name="forward_button">
+          <property name="text">
+           <string/>
+          </property>
+         </widget>
+        </item>
+       </layout>
+      </item>
+     </layout>
+    </widget>
+   </item>
+   <item>
+    <layout class="QHBoxLayout" name="horizontalLayout_6">
+     <item>
+      <widget class="QPushButton" name="buttonClearAll">
+       <property name="text">
+        <string>Clear All</string>
+       </property>
+      </widget>
+     </item>
+     <item>
+      <widget class="QPushButton" name="buttonRestoreDefaults">
+       <property name="text">
+        <string>Restore Defaults</string>
+       </property>
+      </widget>
+     </item>
+     <item>
+      <spacer name="horizontalSpacer_3">
+       <property name="orientation">
+        <enum>Qt::Horizontal</enum>
+       </property>
+       <property name="sizeHint" stdset="0">
+        <size>
+         <width>40</width>
+         <height>20</height>
+        </size>
+       </property>
+      </spacer>
+     </item>
+    </layout>
+   </item>
+   <item>
+    <widget class="QDialogButtonBox" name="buttonBox">
+     <property name="standardButtons">
+      <set>QDialogButtonBox::Cancel|QDialogButtonBox::Ok</set>
+     </property>
+    </widget>
+   </item>
+  </layout>
+ </widget>
+ <resources/>
+ <connections>
+  <connection>
+   <sender>buttonBox</sender>
+   <signal>accepted()</signal>
+   <receiver>ConfigureMouseAdvanced</receiver>
+   <slot>accept()</slot>
+   <hints>
+    <hint type="sourcelabel">
+     <x>124</x>
+     <y>266</y>
+    </hint>
+    <hint type="destinationlabel">
+     <x>124</x>
+     <y>143</y>
+    </hint>
+   </hints>
+  </connection>
+  <connection>
+   <sender>buttonBox</sender>
+   <signal>rejected()</signal>
+   <receiver>ConfigureMouseAdvanced</receiver>
+   <slot>reject()</slot>
+   <hints>
+    <hint type="sourcelabel">
+     <x>124</x>
+     <y>266</y>
+    </hint>
+    <hint type="destinationlabel">
+     <x>124</x>
+     <y>143</y>
+    </hint>
+   </hints>
+  </connection>
+ </connections>
+</ui>