diff --git chrome/browser/download/download_target_determiner.cc chrome/browser/download/download_target_determiner.cc
index 03ca8ad55078..0899131ab154 100644
--- chrome/browser/download/download_target_determiner.cc
+++ chrome/browser/download/download_target_determiner.cc
@@ -540,8 +540,8 @@ void IsHandledBySafePlugin(content::ResourceContext* resource_context,
   content::PluginService* plugin_service =
       content::PluginService::GetInstance();
   bool plugin_found = plugin_service->GetPluginInfo(
-      -1, -1, resource_context, url, url::Origin(), mime_type, false, &is_stale,
-      &plugin_info, &actual_mime_type);
+      -1, -1, resource_context, url, true, url::Origin(), mime_type, false,
+      &is_stale, &plugin_info, &actual_mime_type);
   if (is_stale && stale_plugin_action == RETRY_IF_STALE_PLUGIN_LIST) {
     // The GetPlugins call causes the plugin list to be refreshed. Once that's
     // done we can retry the GetPluginInfo call. We break out of this cycle
diff --git chrome/browser/plugins/chrome_plugin_service_filter.cc chrome/browser/plugins/chrome_plugin_service_filter.cc
index 8e6ef99239ab..24ceaf229702 100644
--- chrome/browser/plugins/chrome_plugin_service_filter.cc
+++ chrome/browser/plugins/chrome_plugin_service_filter.cc
@@ -178,6 +178,7 @@ bool ChromePluginServiceFilter::IsPluginAvailable(
     int render_frame_id,
     const void* context,
     const GURL& plugin_content_url,
+    bool is_main_frame,
     const url::Origin& main_frame_origin,
     content::WebPluginInfo* plugin) {
   base::AutoLock auto_lock(lock_);
diff --git chrome/browser/plugins/chrome_plugin_service_filter.h chrome/browser/plugins/chrome_plugin_service_filter.h
index 133145db74bf..021ab307ee2a 100644
--- chrome/browser/plugins/chrome_plugin_service_filter.h
+++ chrome/browser/plugins/chrome_plugin_service_filter.h
@@ -66,6 +66,7 @@ class ChromePluginServiceFilter : public content::PluginServiceFilter,
                          int render_frame_id,
                          const void* context,
                          const GURL& plugin_content_url,
+                         bool is_main_frame,
                          const url::Origin& main_frame_origin,
                          content::WebPluginInfo* plugin) override;
 
diff --git chrome/browser/plugins/pdf_iframe_navigation_throttle.cc chrome/browser/plugins/pdf_iframe_navigation_throttle.cc
index 3b0948c90a00..f0fb3b5d9d55 100644
--- chrome/browser/plugins/pdf_iframe_navigation_throttle.cc
+++ chrome/browser/plugins/pdf_iframe_navigation_throttle.cc
@@ -53,7 +53,7 @@ PDFIFrameNavigationThrottle::MaybeCreateThrottleFor(
   content::ResourceContext* resource_context =
       handle->GetWebContents()->GetBrowserContext()->GetResourceContext();
   if (filter->IsPluginAvailable(process_id, routing_id, resource_context,
-                                handle->GetURL(), url::Origin(),
+                                handle->GetURL(), false, url::Origin(),
                                 &pdf_plugin_info)) {
     return nullptr;
   }
diff --git chrome/browser/ui/cocoa/drag_util.mm chrome/browser/ui/cocoa/drag_util.mm
index b1a49f718226..cb56c9fd4765 100644
--- chrome/browser/ui/cocoa/drag_util.mm
+++ chrome/browser/ui/cocoa/drag_util.mm
@@ -51,7 +51,7 @@ BOOL IsSupportedFileURL(Profile* profile, const GURL& url) {
   return PluginService::GetInstance()->GetPluginInfo(
       -1,                // process ID
       MSG_ROUTING_NONE,  // routing ID
-      profile->GetResourceContext(), url, url::Origin(), mime_type,
+      profile->GetResourceContext(), url, true, url::Origin(), mime_type,
       allow_wildcard, NULL, &plugin, NULL);
 }
 
diff --git chrome/browser/ui/views/tabs/browser_tab_strip_controller.cc chrome/browser/ui/views/tabs/browser_tab_strip_controller.cc
index f4eb41e948bb..7e47a184d8c0 100644
--- chrome/browser/ui/views/tabs/browser_tab_strip_controller.cc
+++ chrome/browser/ui/views/tabs/browser_tab_strip_controller.cc
@@ -601,6 +601,6 @@ void BrowserTabStripController::OnFindURLMimeTypeCompleted(
           content::PluginService::GetInstance()->GetPluginInfo(
               -1,                // process ID
               MSG_ROUTING_NONE,  // routing ID
-              model_->profile()->GetResourceContext(), url, url::Origin(),
+              model_->profile()->GetResourceContext(), url, true, url::Origin(),
               mime_type, false, NULL, &plugin, NULL));
 }
diff --git content/browser/frame_host/navigation_handle_impl.cc content/browser/frame_host/navigation_handle_impl.cc
index 2986bf0e340e..6ef8486960ce 100644
--- content/browser/frame_host/navigation_handle_impl.cc
+++ content/browser/frame_host/navigation_handle_impl.cc
@@ -368,12 +368,6 @@ net::Error NavigationHandleImpl::GetNetErrorCode() {
 }
 
 RenderFrameHostImpl* NavigationHandleImpl::GetRenderFrameHost() {
-  // TODO(mkwst): Change this to check against 'READY_TO_COMMIT' once
-  // ReadyToCommitNavigation is available whether or not PlzNavigate is
-  // enabled. https://crbug.com/621856
-  CHECK_GE(state_, WILL_PROCESS_RESPONSE)
-      << "This accessor should only be called after a response has been "
-         "delivered for processing.";
   return render_frame_host_;
 }
 
diff --git content/browser/frame_host/render_frame_host_impl.cc content/browser/frame_host/render_frame_host_impl.cc
index 1f566ef1f437..cffef1c8a2f2 100644
--- content/browser/frame_host/render_frame_host_impl.cc
+++ content/browser/frame_host/render_frame_host_impl.cc
@@ -1527,6 +1527,7 @@ void RenderFrameHostImpl::OnDidFailProvisionalLoadWithError(
   if (GetNavigationHandle()) {
     GetNavigationHandle()->set_net_error_code(
         static_cast<net::Error>(params.error_code));
+    GetNavigationHandle()->set_render_frame_host(this);
   }
 
   frame_tree_node_->navigator()->DidFailProvisionalLoadWithError(this, params);
@@ -3269,9 +3270,9 @@ void RenderFrameHostImpl::RegisterMojoInterfaces() {
       &QuotaDispatcherHost::CreateForFrame, GetProcess(), routing_id_));
 
   if (base::FeatureList::IsEnabled(network::features::kNetworkService)) {
-    StoragePartitionImpl* storage_partition =
-        static_cast<StoragePartitionImpl*>(BrowserContext::GetStoragePartition(
-            GetSiteInstance()->GetBrowserContext(), GetSiteInstance()));
+    StoragePartition* storage_partition =
+        BrowserContext::GetStoragePartition(
+            GetSiteInstance()->GetBrowserContext(), GetSiteInstance());
     // TODO(https://crbug.com/813479): Investigate why we need to explicitly
     // specify task runner for BrowserThread::IO here.
     // Bind calls to the BindRegistry should come on to the IO thread by
@@ -3545,9 +3546,9 @@ void RenderFrameHostImpl::CommitNavigation(
     // however only do this for cross-document navigations, because the
     // alternative would be redundant effort.
     network::mojom::URLLoaderFactoryPtrInfo default_factory_info;
-    StoragePartitionImpl* storage_partition =
-        static_cast<StoragePartitionImpl*>(BrowserContext::GetStoragePartition(
-            GetSiteInstance()->GetBrowserContext(), GetSiteInstance()));
+    StoragePartition* storage_partition =
+        BrowserContext::GetStoragePartition(
+            GetSiteInstance()->GetBrowserContext(), GetSiteInstance());
     if (subresource_loader_params &&
         subresource_loader_params->loader_factory_info.is_valid()) {
       // If the caller has supplied a default URLLoaderFactory override (for
@@ -4162,8 +4163,8 @@ void RenderFrameHostImpl::CreateNetworkServiceDefaultFactoryAndObserve(
   auto* context = GetSiteInstance()->GetBrowserContext();
   GetContentClient()->browser()->WillCreateURLLoaderFactory(
       this, false /* is_navigation */, &default_factory_request);
-  StoragePartitionImpl* storage_partition = static_cast<StoragePartitionImpl*>(
-      BrowserContext::GetStoragePartition(context, GetSiteInstance()));
+  StoragePartition* storage_partition =
+      BrowserContext::GetStoragePartition(context, GetSiteInstance());
   if (g_create_network_factory_callback_for_test.Get().is_null()) {
     storage_partition->GetNetworkContext()->CreateURLLoaderFactory(
         std::move(default_factory_request), GetProcess()->GetID());
diff --git content/browser/frame_host/render_frame_message_filter.cc content/browser/frame_host/render_frame_message_filter.cc
index b3653373a51f..6db0652284ec 100644
--- content/browser/frame_host/render_frame_message_filter.cc
+++ content/browser/frame_host/render_frame_message_filter.cc
@@ -546,6 +546,7 @@ void RenderFrameMessageFilter::GetCookies(int render_frame_id,
 
 void RenderFrameMessageFilter::OnGetPlugins(
     bool refresh,
+    bool is_main_frame,
     const url::Origin& main_frame_origin,
     IPC::Message* reply_msg) {
   // Don't refresh if the specified threshold has not been passed.  Note that
@@ -567,18 +568,19 @@ void RenderFrameMessageFilter::OnGetPlugins(
 
   PluginServiceImpl::GetInstance()->GetPlugins(
       base::BindOnce(&RenderFrameMessageFilter::GetPluginsCallback, this,
-                     reply_msg, main_frame_origin));
+                     reply_msg, is_main_frame, main_frame_origin));
 }
 
 void RenderFrameMessageFilter::GetPluginsCallback(
     IPC::Message* reply_msg,
+    bool is_main_frame,
     const url::Origin& main_frame_origin,
     const std::vector<WebPluginInfo>& all_plugins) {
   // Filter the plugin list.
   PluginServiceFilter* filter = PluginServiceImpl::GetInstance()->GetFilter();
   std::vector<WebPluginInfo> plugins;
 
-  int child_process_id = -1;
+  int child_process_id = render_process_id_;
   int routing_id = MSG_ROUTING_NONE;
   // In this loop, copy the WebPluginInfo (and do not use a reference) because
   // the filter might mutate it.
@@ -587,7 +589,7 @@ void RenderFrameMessageFilter::GetPluginsCallback(
     if (!filter ||
         filter->IsPluginAvailable(child_process_id, routing_id,
                                   resource_context_, main_frame_origin.GetURL(),
-                                  main_frame_origin, &plugin)) {
+                                  is_main_frame, main_frame_origin, &plugin)) {
       plugins.push_back(plugin);
     }
   }
@@ -599,6 +601,7 @@ void RenderFrameMessageFilter::GetPluginsCallback(
 void RenderFrameMessageFilter::OnGetPluginInfo(
     int render_frame_id,
     const GURL& url,
+    bool is_main_frame,
     const url::Origin& main_frame_origin,
     const std::string& mime_type,
     bool* found,
@@ -607,8 +610,8 @@ void RenderFrameMessageFilter::OnGetPluginInfo(
   bool allow_wildcard = true;
   *found = plugin_service_->GetPluginInfo(
       render_process_id_, render_frame_id, resource_context_, url,
-      main_frame_origin, mime_type, allow_wildcard, nullptr, info,
-      actual_mime_type);
+      is_main_frame, main_frame_origin, mime_type, allow_wildcard, nullptr,
+      info, actual_mime_type);
 }
 
 void RenderFrameMessageFilter::OnOpenChannelToPepperPlugin(
diff --git content/browser/frame_host/render_frame_message_filter.h content/browser/frame_host/render_frame_message_filter.h
index db9398a07607..ce062d8a9ccd 100644
--- content/browser/frame_host/render_frame_message_filter.h
+++ content/browser/frame_host/render_frame_message_filter.h
@@ -136,13 +136,16 @@ class CONTENT_EXPORT RenderFrameMessageFilter
 
 #if BUILDFLAG(ENABLE_PLUGINS)
   void OnGetPlugins(bool refresh,
+                    bool is_main_frame,
                     const url::Origin& main_frame_origin,
                     IPC::Message* reply_msg);
   void GetPluginsCallback(IPC::Message* reply_msg,
+                          bool is_main_frame,
                           const url::Origin& main_frame_origin,
                           const std::vector<WebPluginInfo>& plugins);
   void OnGetPluginInfo(int render_frame_id,
                        const GURL& url,
+                       bool is_main_frame,
                        const url::Origin& main_frame_origin,
                        const std::string& mime_type,
                        bool* found,
diff --git content/browser/loader/mime_sniffing_resource_handler.cc content/browser/loader/mime_sniffing_resource_handler.cc
index a9322bc8b5d7..0b3bfef2237b 100644
--- content/browser/loader/mime_sniffing_resource_handler.cc
+++ content/browser/loader/mime_sniffing_resource_handler.cc
@@ -494,8 +494,8 @@ bool MimeSniffingResourceHandler::CheckForPluginHandler(
   WebPluginInfo plugin;
   bool has_plugin = plugin_service_->GetPluginInfo(
       info->GetChildID(), info->GetRenderFrameID(), info->GetContext(),
-      request()->url(), url::Origin(), response_->head.mime_type,
-      allow_wildcard, &stale, &plugin, nullptr);
+      request()->url(), info->IsMainFrame(), url::Origin(),
+      response_->head.mime_type, allow_wildcard, &stale, &plugin, nullptr);
 
   if (stale) {
     // Refresh the plugins asynchronously.
diff --git content/browser/plugin_service_impl.cc content/browser/plugin_service_impl.cc
index 130f4d8e92e8..bade33e04c2e 100644
--- content/browser/plugin_service_impl.cc
+++ content/browser/plugin_service_impl.cc
@@ -262,6 +262,7 @@ bool PluginServiceImpl::GetPluginInfo(int render_process_id,
                                       int render_frame_id,
                                       ResourceContext* context,
                                       const GURL& url,
+                                      bool is_main_frame,
                                       const url::Origin& main_frame_origin,
                                       const std::string& mime_type,
                                       bool allow_wildcard,
@@ -278,7 +279,8 @@ bool PluginServiceImpl::GetPluginInfo(int render_process_id,
   for (size_t i = 0; i < plugins.size(); ++i) {
     if (!filter_ ||
         filter_->IsPluginAvailable(render_process_id, render_frame_id, context,
-                                   url, main_frame_origin, &plugins[i])) {
+                                   url, is_main_frame, main_frame_origin,
+                                   &plugins[i])) {
       *info = plugins[i];
       if (actual_mime_type)
         *actual_mime_type = mime_types[i];
diff --git content/browser/plugin_service_impl.h content/browser/plugin_service_impl.h
index e6de4ca6c8b3..18eea4948e43 100644
--- content/browser/plugin_service_impl.h
+++ content/browser/plugin_service_impl.h
@@ -63,6 +63,7 @@ class CONTENT_EXPORT PluginServiceImpl : public PluginService {
                      int render_frame_id,
                      ResourceContext* context,
                      const GURL& url,
+                     bool is_main_frame,
                      const url::Origin& main_frame_origin,
                      const std::string& mime_type,
                      bool allow_wildcard,
diff --git content/common/frame_messages.h content/common/frame_messages.h
index 8e482fa78e3a..99b8e486e88f 100644
--- content/common/frame_messages.h
+++ content/common/frame_messages.h
@@ -1362,8 +1362,9 @@ IPC_MESSAGE_ROUTED1(FrameHostMsg_PepperStopsPlayback,
 
 // Used to get the list of plugins. |main_frame_origin| is used to handle
 // exceptions for plugin content settings.
-IPC_SYNC_MESSAGE_CONTROL2_1(FrameHostMsg_GetPlugins,
+IPC_SYNC_MESSAGE_CONTROL3_1(FrameHostMsg_GetPlugins,
                             bool /* refresh*/,
+                            bool /* is_main_frame */,
                             url::Origin /* main_frame_origin */,
                             std::vector<content::WebPluginInfo> /* plugins */)
 
@@ -1371,9 +1372,10 @@ IPC_SYNC_MESSAGE_CONTROL2_1(FrameHostMsg_GetPlugins,
 // type. If there is no matching plugin, |found| is false.
 // |actual_mime_type| is the actual mime type supported by the
 // found plugin.
-IPC_SYNC_MESSAGE_CONTROL4_3(FrameHostMsg_GetPluginInfo,
+IPC_SYNC_MESSAGE_CONTROL5_3(FrameHostMsg_GetPluginInfo,
                             int /* render_frame_id */,
                             GURL /* url */,
+                            bool /* is_main_frame */,
                             url::Origin /* main_frame_origin */,
                             std::string /* mime_type */,
                             bool /* found */,
diff --git content/ppapi_plugin/ppapi_blink_platform_impl.cc content/ppapi_plugin/ppapi_blink_platform_impl.cc
index bf3c786b5093..ea8f85700e86 100644
--- content/ppapi_plugin/ppapi_blink_platform_impl.cc
+++ content/ppapi_plugin/ppapi_blink_platform_impl.cc
@@ -199,6 +199,7 @@ blink::WebThemeEngine* PpapiBlinkPlatformImpl::ThemeEngine() {
 
 void PpapiBlinkPlatformImpl::GetPluginList(
     bool refresh,
+    bool isMainFrame,
     const blink::WebSecurityOrigin& mainFrameOrigin,
     blink::WebPluginListBuilder* builder) {
   NOTREACHED();
diff --git content/ppapi_plugin/ppapi_blink_platform_impl.h content/ppapi_plugin/ppapi_blink_platform_impl.h
index 8a58a2ae1e2f..21b18ff2eba7 100644
--- content/ppapi_plugin/ppapi_blink_platform_impl.h
+++ content/ppapi_plugin/ppapi_blink_platform_impl.h
@@ -40,6 +40,7 @@ class PpapiBlinkPlatformImpl : public BlinkPlatformImpl {
   blink::WebString DefaultLocale() override;
   blink::WebThemeEngine* ThemeEngine() override;
   void GetPluginList(bool refresh,
+                     bool isMainFrame,
                      const blink::WebSecurityOrigin& mainFrameOrigin,
                      blink::WebPluginListBuilder*) override;
   blink::WebData GetDataResource(const char* name) override;
diff --git content/public/browser/plugin_service.h content/public/browser/plugin_service.h
index ac05c13b1df8..762262bff01a 100644
--- content/public/browser/plugin_service.h
+++ content/public/browser/plugin_service.h
@@ -74,6 +74,7 @@ class PluginService {
                              int render_frame_id,
                              ResourceContext* context,
                              const GURL& url,
+                             bool is_main_frame,
                              const url::Origin& main_frame_origin,
                              const std::string& mime_type,
                              bool allow_wildcard,
diff --git content/public/browser/plugin_service_filter.h content/public/browser/plugin_service_filter.h
index 3b610b1f554e..7c439e060779 100644
--- content/public/browser/plugin_service_filter.h
+++ content/public/browser/plugin_service_filter.h
@@ -33,6 +33,7 @@ class PluginServiceFilter {
                                  int render_frame_id,
                                  const void* context,
                                  const GURL& url,
+                                 bool is_main_frame,
                                  const url::Origin& main_frame_origin,
                                  WebPluginInfo* plugin) = 0;
 
diff --git content/public/renderer/content_renderer_client.h content/public/renderer/content_renderer_client.h
index 34aed4fd3565..364f042ee903 100644
--- content/public/renderer/content_renderer_client.h
+++ content/public/renderer/content_renderer_client.h
@@ -74,6 +74,9 @@ class CONTENT_EXPORT ContentRendererClient {
   // Notifies us that the RenderThread has been created.
   virtual void RenderThreadStarted() {}
 
+  // Notifies that the RenderThread can now send sync IPC messages.
+  virtual void RenderThreadConnected() {}
+
   // Notifies that a new RenderFrame has been created.
   virtual void RenderFrameCreated(RenderFrame* render_frame) {}
 
@@ -333,6 +336,10 @@ class CONTENT_EXPORT ContentRendererClient {
   // This method may invalidate the frame.
   virtual void RunScriptsAtDocumentIdle(RenderFrame* render_frame) {}
 
+  // Notifies that a DevTools agent has attached or detached.
+  virtual void DevToolsAgentAttached() {}
+  virtual void DevToolsAgentDetached() {}
+
   // Allows subclasses to enable some runtime features before Blink has
   // started.
   virtual void SetRuntimeFeaturesDefaultsBeforeBlinkInitialization() {}
diff --git content/public/renderer/render_frame_observer.h content/public/renderer/render_frame_observer.h
index aa77b86eee98..097d26a80aa9 100644
--- content/public/renderer/render_frame_observer.h
+++ content/public/renderer/render_frame_observer.h
@@ -121,6 +121,9 @@ class CONTENT_EXPORT RenderFrameObserver : public IPC::Listener,
   // load. This is used for UseCounter feature metrics.
   virtual void DidObserveNewFeatureUsage(blink::mojom::WebFeature feature) {}
 
+  // Called when this frame gains focus.
+  virtual void FrameFocused() {}
+
   // Called when the focused node has changed to |node|.
   virtual void FocusedNodeChanged(const blink::WebNode& node) {}
 
diff --git content/renderer/render_frame_impl.cc content/renderer/render_frame_impl.cc
index 259d31191208..890ec89bbaee 100644
--- content/renderer/render_frame_impl.cc
+++ content/renderer/render_frame_impl.cc
@@ -3447,7 +3447,8 @@ blink::WebPlugin* RenderFrameImpl::CreatePlugin(
   std::string mime_type;
   bool found = false;
   Send(new FrameHostMsg_GetPluginInfo(
-      routing_id_, params.url, frame_->Top()->GetSecurityOrigin(),
+      routing_id_, params.url, frame_->Parent() == nullptr,
+      frame_->Top()->GetSecurityOrigin(),
       params.mime_type.Utf8(), &found, &info, &mime_type));
   if (!found)
     return nullptr;
@@ -3808,6 +3809,8 @@ void RenderFrameImpl::FrameDetached(DetachType type) {
 
 void RenderFrameImpl::FrameFocused() {
   Send(new FrameHostMsg_FrameFocused(routing_id_));
+  for (auto& observer : observers_)
+    observer.FrameFocused();
 }
 
 void RenderFrameImpl::WillCommitProvisionalLoad() {
diff --git content/renderer/render_thread_impl.cc content/renderer/render_thread_impl.cc
index 81d3f80db8ef..1e349f80ed23 100644
--- content/renderer/render_thread_impl.cc
+++ content/renderer/render_thread_impl.cc
@@ -925,6 +925,8 @@ void RenderThreadImpl::Init(
 
   StartServiceManagerConnection();
 
+  GetContentClient()->renderer()->RenderThreadConnected();
+
   GetAssociatedInterfaceRegistry()->AddInterface(
       base::Bind(&RenderThreadImpl::OnRendererInterfaceRequest,
                  base::Unretained(this)));
diff --git content/renderer/renderer_blink_platform_impl.cc content/renderer/renderer_blink_platform_impl.cc
index 0affacaa0294..8c08aad965a2 100644
--- content/renderer/renderer_blink_platform_impl.cc
+++ content/renderer/renderer_blink_platform_impl.cc
@@ -849,6 +849,7 @@ RendererBlinkPlatformImpl::CreateMIDIAccessor(
 
 void RendererBlinkPlatformImpl::GetPluginList(
     bool refresh,
+    bool isMainFrame,
     const blink::WebSecurityOrigin& mainFrameOrigin,
     blink::WebPluginListBuilder* builder) {
 #if BUILDFLAG(ENABLE_PLUGINS)
@@ -856,7 +857,8 @@ void RendererBlinkPlatformImpl::GetPluginList(
   if (!plugin_refresh_allowed_)
     refresh = false;
   RenderThread::Get()->Send(
-      new FrameHostMsg_GetPlugins(refresh, mainFrameOrigin, &plugins));
+      new FrameHostMsg_GetPlugins(refresh, isMainFrame, mainFrameOrigin,
+                                  &plugins));
   for (const WebPluginInfo& plugin : plugins) {
     builder->AddPlugin(WebString::FromUTF16(plugin.name),
                        WebString::FromUTF16(plugin.desc),
@@ -1417,6 +1419,14 @@ void RendererBlinkPlatformImpl::RequestPurgeMemory() {
   base::MemoryCoordinatorClientRegistry::GetInstance()->PurgeMemory();
 }
 
+void RendererBlinkPlatformImpl::DevToolsAgentAttached() {
+  GetContentClient()->renderer()->DevToolsAgentAttached();
+}
+
+void RendererBlinkPlatformImpl::DevToolsAgentDetached() {
+  GetContentClient()->renderer()->DevToolsAgentDetached();
+}
+
 void RendererBlinkPlatformImpl::InitializeWebDatabaseHostIfNeeded() {
   if (!web_database_host_) {
     web_database_host_ = blink::mojom::ThreadSafeWebDatabaseHostPtr::Create(
diff --git content/renderer/renderer_blink_platform_impl.h content/renderer/renderer_blink_platform_impl.h
index e8a4578009d1..780d8b29acb2 100644
--- content/renderer/renderer_blink_platform_impl.h
+++ content/renderer/renderer_blink_platform_impl.h
@@ -128,6 +128,7 @@ class CONTENT_EXPORT RendererBlinkPlatformImpl : public BlinkPlatformImpl {
   viz::FrameSinkId GenerateFrameSinkId() override;
 
   void GetPluginList(bool refresh,
+                     bool isMainFrame,
                      const blink::WebSecurityOrigin& mainFrameOrigin,
                      blink::WebPluginListBuilder* builder) override;
   blink::WebPublicSuffixList* PublicSuffixList() override;
@@ -256,6 +257,9 @@ class CONTENT_EXPORT RendererBlinkPlatformImpl : public BlinkPlatformImpl {
       mojo::ScopedDataPipeConsumerHandle handle) override;
   void RequestPurgeMemory() override;
 
+  void DevToolsAgentAttached() override;
+  void DevToolsAgentDetached() override;
+
   // Returns non-null.
   // It is invalid to call this in an incomplete env where
   // RenderThreadImpl::current() returns nullptr (e.g. in some tests).
diff --git content/shell/browser/shell_plugin_service_filter.cc content/shell/browser/shell_plugin_service_filter.cc
index 3a48c59b7e3e..d10ef64adbba 100644
--- content/shell/browser/shell_plugin_service_filter.cc
+++ content/shell/browser/shell_plugin_service_filter.cc
@@ -18,6 +18,7 @@ bool ShellPluginServiceFilter::IsPluginAvailable(
     int render_frame_id,
     const void* context,
     const GURL& url,
+    bool is_main_frame,
     const url::Origin& main_frame_origin,
     WebPluginInfo* plugin) {
   return plugin->name == base::ASCIIToUTF16("Blink Test Plugin") ||
diff --git content/shell/browser/shell_plugin_service_filter.h content/shell/browser/shell_plugin_service_filter.h
index 7767a620a9fd..8a95377f5f3b 100644
--- content/shell/browser/shell_plugin_service_filter.h
+++ content/shell/browser/shell_plugin_service_filter.h
@@ -21,6 +21,7 @@ class ShellPluginServiceFilter : public PluginServiceFilter {
                          int render_frame_id,
                          const void* context,
                          const GURL& url,
+                         bool is_main_frame,
                          const url::Origin& main_frame_origin,
                          WebPluginInfo* plugin) override;
 
diff --git content/test/fake_plugin_service.cc content/test/fake_plugin_service.cc
index 6746b9f16e7e..8634ada48d57 100644
--- content/test/fake_plugin_service.cc
+++ content/test/fake_plugin_service.cc
@@ -29,6 +29,7 @@ bool FakePluginService::GetPluginInfo(int render_process_id,
                                       int render_frame_id,
                                       ResourceContext* context,
                                       const GURL& url,
+                                      bool is_main_frame,
                                       const url::Origin& main_frame_origin,
                                       const std::string& mime_type,
                                       bool allow_wildcard,
diff --git content/test/fake_plugin_service.h content/test/fake_plugin_service.h
index db23a83ed079..57a4c536118c 100644
--- content/test/fake_plugin_service.h
+++ content/test/fake_plugin_service.h
@@ -30,6 +30,7 @@ class FakePluginService : public PluginService {
                      int render_frame_id,
                      ResourceContext* context,
                      const GURL& url,
+                     bool is_main_frame,
                      const url::Origin& main_frame_origin,
                      const std::string& mime_type,
                      bool allow_wildcard,
diff --git content/test/test_blink_web_unit_test_support.cc content/test/test_blink_web_unit_test_support.cc
index 25182fdb0928..9cc19c4016d3 100644
--- content/test/test_blink_web_unit_test_support.cc
+++ content/test/test_blink_web_unit_test_support.cc
@@ -324,6 +324,7 @@ blink::WebThread* TestBlinkWebUnitTestSupport::CurrentThread() {
 
 void TestBlinkWebUnitTestSupport::GetPluginList(
     bool refresh,
+    bool is_main_frame,
     const blink::WebSecurityOrigin& mainFrameOrigin,
     blink::WebPluginListBuilder* builder) {
   builder->AddPlugin("pdf", "pdf", "pdf-files");
diff --git content/test/test_blink_web_unit_test_support.h content/test/test_blink_web_unit_test_support.h
index d8ad7b6e4435..5eda4bc3c2d5 100644
--- content/test/test_blink_web_unit_test_support.h
+++ content/test/test_blink_web_unit_test_support.h
@@ -72,6 +72,7 @@ class TestBlinkWebUnitTestSupport : public BlinkPlatformImpl {
       const blink::WebSize& size) override;
 
   void GetPluginList(bool refresh,
+                     bool is_main_frame,
                      const blink::WebSecurityOrigin& mainFrameOrigin,
                      blink::WebPluginListBuilder* builder) override;