diff --git chrome/browser/app_controller_mac.mm chrome/browser/app_controller_mac.mm
index c7780ede01c83..6b856949d3c0a 100644
--- chrome/browser/app_controller_mac.mm
+++ chrome/browser/app_controller_mac.mm
@@ -31,6 +31,7 @@
 #include "base/threading/scoped_blocking_call.h"
 #include "base/threading/thread_restrictions.h"
 #include "build/branding_buildflags.h"
+#include "cef/libcef/features/features.h"
 #include "chrome/app/chrome_command_ids.h"
 #include "chrome/browser/apps/app_shim/app_shim_manager_mac.h"
 #include "chrome/browser/apps/app_shim/app_shim_termination_manager.h"
@@ -1290,6 +1291,7 @@ static base::mac::ScopedObjCClassSwizzler* g_swizzle_imk_input_session;
 
 // Run a (background) application in a new tab.
 - (void)executeApplication:(id)sender {
+#if BUILDFLAG(ENABLE_BACKGROUND_MODE)
   NSInteger tag = [sender tag];
   Profile* profile = [self lastProfile];
   DCHECK(profile);
@@ -1298,6 +1300,7 @@ static base::mac::ScopedObjCClassSwizzler* g_swizzle_imk_input_session;
          tag < static_cast<int>(applications.size()));
   const extensions::Extension* extension = applications.GetExtension(tag);
   BackgroundModeManager::LaunchBackgroundApplication(profile, extension);
+#endif  // BUILDFLAG(ENABLE_BACKGROUND_MODE)
 }
 
 // Same as |-commandDispatch:|, but executes commands using a disposition
@@ -1693,6 +1696,7 @@ static base::mac::ScopedObjCClassSwizzler* g_swizzle_imk_input_session;
   // TODO(rickcam): Mock out BackgroundApplicationListModel, then add unit
   // tests which use the mock in place of the profile-initialized model.
 
+#if BUILDFLAG(ENABLE_BACKGROUND_MODE)
   // Avoid breaking unit tests which have no profile.
   if (profile) {
     BackgroundApplicationListModel applications(profile);
@@ -1719,6 +1723,7 @@ static base::mac::ScopedObjCClassSwizzler* g_swizzle_imk_input_session;
       }
     }
   }
+#endif  // BUILDFLAG(ENABLE_BACKGROUND_MODE)
 
   return dockMenu;
 }
@@ -1948,11 +1953,13 @@ static base::mac::ScopedObjCClassSwizzler* g_swizzle_imk_input_session;
 namespace {
 
 void UpdateProfileInUse(Profile* profile, Profile::CreateStatus status) {
+#if !BUILDFLAG(ENABLE_CEF)
   if (status == Profile::CREATE_STATUS_INITIALIZED) {
     AppController* controller =
         base::mac::ObjCCastStrict<AppController>([NSApp delegate]);
     [controller windowChangedToProfile:profile];
   }
+#endif  // !BUILDFLAG(ENABLE_CEF)
 }
 
 }  // namespace
diff --git chrome/browser/browser_process.h chrome/browser/browser_process.h
index 3d634db18900a..96e44ad48e5e5 100644
--- chrome/browser/browser_process.h
+++ chrome/browser/browser_process.h
@@ -197,9 +197,9 @@ class BrowserProcess {
   virtual DownloadStatusUpdater* download_status_updater() = 0;
   virtual DownloadRequestLimiter* download_request_limiter() = 0;
 
+#if BUILDFLAG(ENABLE_BACKGROUND_MODE)
   // Returns the object that manages background applications.
   virtual BackgroundModeManager* background_mode_manager() = 0;
-#if BUILDFLAG(ENABLE_BACKGROUND_MODE)
   virtual void set_background_mode_manager_for_test(
       std::unique_ptr<BackgroundModeManager> manager) = 0;
 #endif
diff --git chrome/browser/browser_process_impl.cc chrome/browser/browser_process_impl.cc
index cce917cdc65db..5da3a16aef1c7 100644
--- chrome/browser/browser_process_impl.cc
+++ chrome/browser/browser_process_impl.cc
@@ -952,18 +952,14 @@ DownloadRequestLimiter* BrowserProcessImpl::download_request_limiter() {
   return download_request_limiter_.get();
 }
 
-BackgroundModeManager* BrowserProcessImpl::background_mode_manager() {
 #if BUILDFLAG(ENABLE_BACKGROUND_MODE)
+BackgroundModeManager* BrowserProcessImpl::background_mode_manager() {
   DCHECK_CALLED_ON_VALID_SEQUENCE(sequence_checker_);
   if (!background_mode_manager_)
     CreateBackgroundModeManager();
   return background_mode_manager_.get();
-#else
-  return nullptr;
-#endif
 }
 
-#if BUILDFLAG(ENABLE_BACKGROUND_MODE)
 void BrowserProcessImpl::set_background_mode_manager_for_test(
     std::unique_ptr<BackgroundModeManager> manager) {
   background_mode_manager_ = std::move(manager);
diff --git chrome/browser/browser_process_impl.h chrome/browser/browser_process_impl.h
index b4ceefbccd083..7d60206c83b13 100644
--- chrome/browser/browser_process_impl.h
+++ chrome/browser/browser_process_impl.h
@@ -169,8 +169,8 @@ class BrowserProcessImpl : public BrowserProcess,
   void SetApplicationLocale(const std::string& actual_locale) override;
   DownloadStatusUpdater* download_status_updater() override;
   DownloadRequestLimiter* download_request_limiter() override;
-  BackgroundModeManager* background_mode_manager() override;
 #if BUILDFLAG(ENABLE_BACKGROUND_MODE)
+  BackgroundModeManager* background_mode_manager() override;
   void set_background_mode_manager_for_test(
       std::unique_ptr<BackgroundModeManager> manager) override;
 #endif
diff --git chrome/browser/lifetime/browser_close_manager.cc chrome/browser/lifetime/browser_close_manager.cc
index e0cafee5eedd6..06ded156be3cc 100644
--- chrome/browser/lifetime/browser_close_manager.cc
+++ chrome/browser/lifetime/browser_close_manager.cc
@@ -148,12 +148,14 @@ void BrowserCloseManager::CloseBrowsers() {
   // exit can restore all browsers open before exiting.
   ProfileManager::ShutdownSessionServices();
 #endif
+#if BUILDFLAG(ENABLE_BACKGROUND_MODE)
   if (!browser_shutdown::IsTryingToQuit()) {
     BackgroundModeManager* background_mode_manager =
         g_browser_process->background_mode_manager();
     if (background_mode_manager)
       background_mode_manager->SuspendBackgroundMode();
   }
+#endif
 
   // Make a copy of the BrowserList to simplify the case where we need to
   // destroy a Browser during the loop.