diff --git chrome/browser/download/chrome_download_manager_delegate.cc chrome/browser/download/chrome_download_manager_delegate.cc
index 447e7d0d5dc6d..7bba632f1331c 100644
--- chrome/browser/download/chrome_download_manager_delegate.cc
+++ chrome/browser/download/chrome_download_manager_delegate.cc
@@ -146,6 +146,10 @@
 #include "chrome/browser/safe_browsing/download_protection/download_protection_util.h"
 #endif
 
+#if BUILDFLAG(ENABLE_CEF)
+#include "cef/libcef/browser/download_manager_delegate.h"
+#endif
+
 using content::BrowserThread;
 using content::DownloadManager;
 using download::DownloadItem;
@@ -490,6 +494,11 @@ ChromeDownloadManagerDelegate::ChromeDownloadManagerDelegate(Profile* profile)
   download_dialog_bridge_ = std::make_unique<DownloadDialogBridge>();
   download_message_bridge_ = std::make_unique<DownloadMessageBridge>();
 #endif
+
+#if BUILDFLAG(ENABLE_CEF)
+  cef_delegate_ =
+      cef::DownloadManagerDelegate::Create(profile_->GetDownloadManager());
+#endif
 }
 
 ChromeDownloadManagerDelegate::~ChromeDownloadManagerDelegate() {
@@ -549,6 +558,9 @@ void ChromeDownloadManagerDelegate::Shutdown() {
     download_manager_->RemoveObserver(this);
     download_manager_ = nullptr;
   }
+#if BUILDFLAG(ENABLE_CEF)
+  cef_delegate_.reset();
+#endif
 }
 
 void ChromeDownloadManagerDelegate::OnDownloadCanceledAtShutdown(
@@ -617,6 +629,12 @@ bool ChromeDownloadManagerDelegate::DetermineDownloadTarget(
     ReportPDFLoadStatus(PDFLoadStatus::kTriggeredNoGestureDriveByDownload);
   }
 
+#if BUILDFLAG(ENABLE_CEF)
+  if (cef_delegate_->DetermineDownloadTarget(download, callback)) {
+    return true;
+  }
+#endif
+
   DownloadTargetDeterminer::CompletionCallback target_determined_callback =
       base::BindOnce(&ChromeDownloadManagerDelegate::OnDownloadTargetDetermined,
                      weak_ptr_factory_.GetWeakPtr(), download->GetId(),
diff --git chrome/browser/download/chrome_download_manager_delegate.h chrome/browser/download/chrome_download_manager_delegate.h
index e2cf12d2c8fee..376818e28798c 100644
--- chrome/browser/download/chrome_download_manager_delegate.h
+++ chrome/browser/download/chrome_download_manager_delegate.h
@@ -19,6 +19,7 @@
 #include "base/task/sequenced_task_runner.h"
 #include "base/unguessable_token.h"
 #include "build/build_config.h"
+#include "cef/libcef/features/runtime.h"
 #include "chrome/browser/download/download_completion_blocker.h"
 #include "chrome/browser/download/download_target_determiner_delegate.h"
 #include "components/download/public/common/download_danger_type.h"
@@ -57,6 +58,12 @@ class CrxInstallError;
 }
 #endif
 
+#if BUILDFLAG(ENABLE_CEF)
+namespace cef {
+class DownloadManagerDelegate;
+}
+#endif
+
 // This is the Chrome side helper for the download system.
 class ChromeDownloadManagerDelegate
     : public content::DownloadManagerDelegate,
@@ -387,6 +394,10 @@ class ChromeDownloadManagerDelegate
   // Whether a file picker dialog is showing.
   bool is_file_picker_showing_;
 
+#if BUILDFLAG(ENABLE_CEF)
+  std::unique_ptr<cef::DownloadManagerDelegate> cef_delegate_;
+#endif
+
   base::WeakPtrFactory<ChromeDownloadManagerDelegate> weak_ptr_factory_{this};
 };
 
diff --git chrome/browser/download/download_prefs.cc chrome/browser/download/download_prefs.cc
index 773f72da82f90..0043dd530934d 100644
--- chrome/browser/download/download_prefs.cc
+++ chrome/browser/download/download_prefs.cc
@@ -23,6 +23,7 @@
 #include "base/strings/utf_string_conversions.h"
 #include "build/build_config.h"
 #include "build/chromeos_buildflags.h"
+#include "cef/libcef/features/runtime.h"
 #include "chrome/browser/download/chrome_download_manager_delegate.h"
 #include "chrome/browser/download/download_core_service_factory.h"
 #include "chrome/browser/download/download_core_service_impl.h"
@@ -64,6 +65,10 @@
 #include "chrome/browser/flags/android/chrome_feature_list.h"
 #endif
 
+#if BUILDFLAG(ENABLE_ALLOY_BOOTSTRAP)
+#include "cef/libcef/browser/alloy/alloy_download_util.h"
+#endif
+
 using content::BrowserContext;
 using content::BrowserThread;
 using content::DownloadManager;
@@ -355,6 +360,11 @@ DownloadPrefs* DownloadPrefs::FromDownloadManager(
 // static
 DownloadPrefs* DownloadPrefs::FromBrowserContext(
     content::BrowserContext* context) {
+#if BUILDFLAG(ENABLE_ALLOY_BOOTSTRAP)
+  if (cef::IsAlloyRuntimeEnabled()) {
+    return alloy::GetDownloadPrefsFromBrowserContext(context);
+  }
+#endif
   return FromDownloadManager(context->GetDownloadManager());
 }