diff --git a/patch/patch.cfg b/patch/patch.cfg
index 453333f1b..d0eea34f4 100644
--- a/patch/patch.cfg
+++ b/patch/patch.cfg
@@ -226,6 +226,10 @@ patches = [
     #
     # Linux: Fix duplicate symbol error for window_frame_util.cc
     # https://issuetracker.google.com/issues/343037853#comment3
+    #
+    # Avoid duplicate window from DevTools when CEF handles the open via
+    # OnOpenURLFromTab.
+    # https://github.com/chromiumembedded/cef/issues/3735
     'name': 'chrome_browser_browser',
   },
   {
diff --git a/patch/patches/chrome_browser_browser.patch b/patch/patches/chrome_browser_browser.patch
index dba6263b3..4d772a54e 100644
--- a/patch/patches/chrome_browser_browser.patch
+++ b/patch/patches/chrome_browser_browser.patch
@@ -13,7 +13,7 @@ index 2480282a19d12..dbd1fbf8a15b5 100644
    return false;
  }
 diff --git chrome/browser/devtools/devtools_window.cc chrome/browser/devtools/devtools_window.cc
-index 02ff1e580d3a7..7f51115896049 100644
+index 02ff1e580d3a7..e2e232c424029 100644
 --- chrome/browser/devtools/devtools_window.cc
 +++ chrome/browser/devtools/devtools_window.cc
 @@ -37,6 +37,7 @@
@@ -38,7 +38,21 @@ index 02ff1e580d3a7..7f51115896049 100644
    }
  
    // Create WebContents with devtools.
-@@ -1919,12 +1927,28 @@ void DevToolsWindow::CreateDevToolsBrowser() {
+@@ -1754,9 +1762,13 @@ void DevToolsWindow::OpenInNewTab(const GURL& url) {
+   if (!inspected_web_contents ||
+       !inspected_web_contents->OpenURL(params,
+                                        /*navigation_handle_callback=*/{})) {
++#if !BUILDFLAG(ENABLE_CEF)
++    // Remove default behavior when CEF handles the open via OnOpenURLFromTab.
++    // See CEF issue #3735.
+     chrome::ScopedTabbedBrowserDisplayer displayer(profile_);
+     chrome::AddSelectedTabWithURL(displayer.browser(), fixed_url,
+                                   ui::PAGE_TRANSITION_LINK);
++#endif
+   }
+ }
+ 
+@@ -1919,12 +1931,28 @@ void DevToolsWindow::CreateDevToolsBrowser() {
        Browser::CreationStatus::kOk) {
      return;
    }