diff --git a/libcef/browser/frame_host_impl.cc b/libcef/browser/frame_host_impl.cc
index bae40ec80..7b2f6056f 100644
--- a/libcef/browser/frame_host_impl.cc
+++ b/libcef/browser/frame_host_impl.cc
@@ -367,6 +367,11 @@ void CefFrameHostImpl::SendCommand(
   if (frame_id < CefFrameHostImpl::kMainFrameId)
     return;
 
+  if (!render_frame_host_ || !response_manager_) {
+    // detached frame has no response_manager_
+    return;
+  }
+
   TRACE_EVENT2("cef", "CefFrameHostImpl::SendCommand", "frame_id", frame_id,
                "needsResponse", responseHandler.get() ? 1 : 0);
   Cef_Request_Params params;
@@ -407,6 +412,11 @@ void CefFrameHostImpl::SendCode(
   if (frame_id < CefFrameHostImpl::kMainFrameId)
     return;
 
+  if (!render_frame_host_ || !response_manager_) {
+    // detached frame has no response_manager_
+    return;
+  }
+
   TRACE_EVENT2("cef", "CefFrameHostImpl::SendCommand", "frame_id", frame_id,
                "needsResponse", responseHandler.get() ? 1 : 0);
   Cef_Request_Params params;